Indication

Allergic and inflammatory conditions of the eye

Adult dose

Adults: Instill 1-2 drops into conjunctival sac 2-3 times daily. Dose may be increased to 1 drop hourly during first 24-48 hr.

Child dose

Children (above 2 years of age): Instill 1-2 drops into conjunctival sac 2-3 times daily. Dose may be increased to 1 drop hourly during first 24-48 hr.

Contraindication

Viral diseases of the cornea and conjunctiva, including epithelial herpes simplex keratitis (dendritic keratitis), Vaccinia and Varicella, mycobacterial eye infection, ocular fungal infections, untreated eye infections; hypersensitivity.

Mode of action

Fluorometholone suppresses the migration of polymorphonuclear leukocytes and reversal of increased capillary permeability thus decreasing inflammation.

Precaution

Glaucoma (check intraocular pressure periodically), history of herpes simplex fungal or bacterial infections. Not to be used in mustard gas keratitis and Sjogren's keratoconjunctivitis. May cause corneal and scleral thinning which may lead to perforation in serious cases. Use of steroids after cataract surgery may prolong healing time and increase bleb formation. Pregnancy, lactation; children <2 yr.

Side effect

Mild burning sensation, reversible increase in intra ocular pressure (IOP), reactive hyperemia/rebound effect, cataract & corneal defects, glaucoma, systemic effects (chronic use).

Pregnancy category

Note : C Lactation: Excretion in milk unknown; not recommended